Vitamin E Polyethylene Glycol Succinate TPGS Powder

TPGS stands for Tocopheryl Polyethylene Glycol 1000 Succinate. It is a water-soluble, nonionic vitamin E derivative. TPGS is derived from natural vitamin E and modified to improve its solubility in aqueous systems. It is commonly available in the form of yellow to light brown powder.

CAS #:
9002-96-4
Certificates:
GMP/Kosher/Halal/USDFM
Specifications:
USP/BP/EP
Payment:
L/C,T/T,D/P,Western Union,Paypal,Money Gram

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Product Detail

Description

Name	TPGS Powder
Other Name	VITAMINETPGS; Vitamin E polyethyl eneglycol succinate; Tocophersolan; D-a-Tocopherol Polyethylene Glycol Succinate (Vitamin ETPGS)
CAS No.	9002-96-4
Molecular formula	(C2H4O)nC33H54O5
Melting point	34-38°C
Storage conditions	2-8°C
Solubility	H2O: soluble1g/10 mL, clear to faintly turbid, colorless to faintly yellow
Appearance	Solid
Color	White to Pale Yellow Waxy

Function
TPGS has several important functions in various industries. Firstly, it acts as a solubilizer and emulsifier, helping to enhance the solubility and stability of poorly water-soluble drugs and nutraceuticals in aqueous environments. Secondly, TPGS exhibits excellent antioxidant properties, which can protect sensitive compounds from oxidation and degradation. Additionally, TPGS has been found to enhance drug absorption through various mechanisms, including inhibition of efflux transporters and improvement of mucosal permeability.

Application

Medicinal Field:
It is mainly used as excipient and absorption enhancer. Due to its emulsifying and solubilizing effects, it can effectively improve the bioavailability of drugs. Thus, it can reduce the amount of drug use and reduce the toxic side effects of drugs.
1. Anti-tumor drug: FDA approved paclitaxel emulsion formulation (Sonus Pharmaceuticals)
2. Anti-HIV drugs: Agenerase (Amprenavir) and APTIVUS (Telanavir).
3. Anti-hepatitis C virus (HCV) drugs: VIEKERA Pack tablets.
4. Ophthalmic medications: dry eye; prevention of contact lens wear; healing of the postoperative cornea.
5. Treatment of vitamin E deficiency caused by chronic bile deficiency.

Food and Cosmetics Field:

1. Converts a wide range of natural nutrients into stable, water-soluble liquids or powders.

2. Has antioxidant and anti-aging effects.

FAQ:

1. Are you a manufacturer or a trading company?
A: We are a manufacturer and welcome you to visit our factory.

2. How to confirm the product quality before placing an order?
A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency.

3. What's your MOQ?
A: It depends on different products. We accept sample orders. Also, for some products, we can provide you with a free sample.

4. Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.

5. How about delivery time and method?
A: We usually ship within 3-5 working days after payment.
We can make ships by sea, air, and express. Also , it can make door-to-door shipping.

6. How to solve the after-sales disputes?
A: We accept changing or refunding services if there is any quality problem.

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Subject : Vitamin E Polyethylene Glycol Succinate TPGS Powder

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